After adjusting for all other significant outcome predictors (age, the NIHSS score, atrial fibrillation, small-vessel occlusive etiology, white cell count, and HDL cholesterol, triglyceride, CRP, fT3 levels) transthyretin was still an independent (P <0.05) outcome predictor with an adjusted OR of 0.96 (95% CI, 0.9–0.99). The gene discussed is CRP; the disease is atrial fibrillation.