GPT and obesity due to melanocortin 4 receptor deficiency: According to BMI and AST/ALT ratio, subjects were stratified in 3 groups: normal weight group (P15th to P85th of the WHO Child Growth Standards [17] and AST/ALT ratio > 1); obesity group (P > 95th and AST/ALT ratio > 1); and obesity group with hepatic steatosis (P > 95th and AST/ALT ratio < 1).