Sulfate conjugation by other SULT enzymes (SULT1A3, SULT1E1 and SULT1B1) may result in the activation or inactivation of anti-cancer drugs (e.g., raloxifene, sesamol, fulvestrant, and resveratrol), thereby affecting their anti-tumor effects10–13. The gene discussed is SULT1B1; the disease is neoplasm.