NPPB and Hyperkalemia: It was found that once-daily oral administration of 5 and 10 mg of finerenone were at least as effective as spironolactone (25 or 50 mg/day) in decreasing BNP, NT-pro-BNP and urinary albumin, but were associated with significantly lower increases in serum potassium, a significantly lower incidence of hyperkalemia as well as a lower incidence of worsening renal function (Pitt et al. 2013).