Treatment of the samples with free EpCAM BiTE and the EpCAM BiTE‐expressing viruses led to strong T‐cell activation (measured by CD25 expression), and a depletion of EpCAM‐positive tumour cells to background levels, although FAP‐positive (EpCAM‐negative) fibroblasts showed no change in numbers. The gene discussed is FAP; the disease is neoplasm.