Although UTUC has been found to have similar genetic mutations as UCB [27], a recent genomic characterization of UTUC by Sfakanios et al. [28] reported significant differences in the prevalence of certain mutations, e.g., FGFR3 mutations are more common in UTUC whereas mutations in TP53 are more common in UCB. The gene discussed is FGFR3; the disease is renal pelvis/ureter urothelial carcinoma.