Annexin V and PI staining demonstrated a significant decrease in the number of apoptotic events in both pancreatic cancer cell lines that were cultured in omental fat CM compared with RM, specifically, 5.2% versus 18.6% (P< .001) in the PANC-1 cells (Fig 3B) and 5.5% versus 14.7% (P< .001) in the MIA-PaCa-2 cells (Fig 3C). Here, ANXA5 is linked to familial pancreatic carcinoma.