Results showed that DR has no relationship to gender, BMI, Triglycerides, TCH, HDL, LDL, and hypertension but DR was positively correlated with glucose, HbA1C, sVCAM-1, CTRP3, and CTRP5 (Table 2 and Table B in S1 File). The gene discussed is C1QTNF3; the disease is hypertensive disorder.