The NAS in MCD mice liver revealed scores of 2.3 ± 0.4, 1.8 ± 0.3, and 1.3 ± 0.4 points for steatosis, centrilobular hepatitis, and ballooning degeneration, respectively, whereas the value for each category was significantly decreased by 0.5 ± 0.5 points in MCD + FOS mice (steatosis, p = 0.003; centrilobular hepatitis, p = 0.005; ballooning degeneration, p = 0.03; Fig 2c). Here, FOS is linked to Hepatitis.