Furthermore, a recent study by Simbolo et al. [31] has also shown that rare lung LCNECs resembling carcinoids harbour MEN1 mutations—the most frequent alteration in ACs—along with TERT, SDHA, RICTOR, PIK3CA, MYCL and SRC gains are shared with high-grade carcinomas. The gene discussed is PIK3CA; the disease is carcinoid tumor.