ARID1B is associated with the Coffin-Siris syndrome [26–28], and the clinical features of the patient 2 are compatible with this diagnosis (mainly the neonatal eating disorders, ID, motor and speech delay, hypertrichosis, synophrys, dystrophic toenails, clinodactyly, and short fingers). Here, ARID1B is linked to Coffin-Siris syndrome.