Notably, ABCG2 mRNA expression levels of the high and middle doses of chicory were increased to 231.34% and 383.17% in jejunum, and protein expression levels of them in jejunum were markedly enhanced to 153.98% and 199.33% by western blotting, when compared with hyperuricemia rats respectively. The gene discussed is ABCG2; the disease is hyperuricemia.