ACTA1 and focal segmental glomerulosclerosis: In the Shenshu moxibustion and Geshu moxibustion groups, the above indexes were relatively lower than in the FSGS model group, while expression of renal α-SMA and FN of the Geshu moxibustion group was lower than the losartan group, suggesting that Shenshu moxibustion, Geshu moxibustion, and losartan treatment improve the renal interstitial fibrosis of FSGS rats.