Our previous studies have shown that DJC can reverse STZ-induced DN in rats, reduce urinary protein and urine microalbumin, decrease the serum levels of MCP-1, TGFβ1, TNF-α, CXCL-5, and CXCL-7, inhibit the inflammatory reaction, and improve the microinflammatory state [12–14]. This evidence concerns the gene TGFB1 and liver dysplastic nodule.