Our 3 NBAS-disease patients clinically resembled one another: all suffered from a febrile illness, likely infective (viral / bacterial) before each episode of RALF (fever-related RALF), with markedly elevated ALT (77–9382 IU/L; normal 0–40) and AST (213–17,344 IU/L; normal 0–40) activities 24-72 h after elevation of body temperature, succeeded by severe coagulopathy (maximum INR = 6.89; normal 0.8–1.2) and mild to moderate jaundice that were ascribed to ALF. The gene discussed is GPT; the disease is Jaundice.