Other targets that showed altered expression in African-American ESCC include genes with a wide range of function: MGST2, ABCC1, ABCC5, GCLC GPX4, ACOX1, BLVRA, FTL1, CEBPB, ACLY, ELOVL5, FABP5, ACAA1B. The gene discussed is GPX4; the disease is esophageal squamous cell carcinoma.