ACTA2 and idiopathic pulmonary fibrosis: Moreover, the reduction in Collagen 1a and αSMA levels on the plastic surface (Fig. 1e-f) was also completely prevented (fold change of IPF-SN vs. control: 0.97 ± 0.05 and 1.06 ± 0.12 for COL1A and ACTA2, respectively, n = 4).