TGFB1 and neoplasm: On the other hand, inhibitors of β-catenin or TGF-β signalling, ICG-001 and LY2157299, respectively, when administered in combination, exhibited remarkable inhibitory effects, similar to that of miR-128-3p antagonism, on tumour growth and spontaneous/experimental metastasis of A549-luc-CDDP-4th cells, whereas ICG-001 or LY2157299 treatment alone also to certain degrees displayed therapeutic effects (Fig. 6d,e, g and Supplementary Fig. 8b).