CCND1 and non-small cell lung carcinoma: However, although miR-128-3p upregulated the expression of cyclin D1 (CCND1), a critical driver for tumour cell proliferation, silencing cyclin D1 in miR-128-3p-overexpressing NSCLC cells barely influenced their ability to migrate, whereas significantly deteriorated their cell proliferation andsurvival (Supplementary Fig. 3j–l), suggesting that the observed miR-128-3p-induced migration is not affected by its promotion of cellular proliferation and survival.