2002), a protein located between inner membrane leaflet and cytoskeleton that plays a key role in a range of distinct cellular processes including cell motility (Neisch & Fehon, 2011). Intriguingly, ezrin is overexpressed in a number of distinct cancers (Clucas & Valderrama, 2014), where it correlates with invasiveness, cell migration and metastasis (Moleirinho et al. 2013), and in the context of MB has been identified as a risk factor (Park et al. 2003; Osawa et al. 2009). This evidence concerns the gene EZR and cancer.