POU5F1 and neoplasm: (Pro)renin receptor (PRR), angiotensin II receptor 1 (ATIIR1), and angiotensin II receptor 2 (ATIIR2) are expressed by two CSC subpopulations within OTSCC: one within the tumor nests that express SALL4 and another within the peritumoral stroma that express OCT4 (87).