The major anti-cancer compound in turmeric is curcumin ((1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione) which has been able to suppress many biological factors responsible for the proliferation of cancer cells, for instance NF-kB, IkBα kinase, by induction in apoptosis pathway through activation of caspase-8, BID cleavage and cytochrome C release in human lung, breast, prostate tumor cell lines and many myeloma cells [2], [3], [4], [5], [6], [7], [8]. The gene discussed is CASP8; the disease is cancer.