Also reverse docking studies performed on [6]-gingerol with leukotriene A4 hydrolase (LTA4H) as target for cancer therapy confirmed that this compound has binding similarities like bestatin (the aminopeptide inhibitor) which binds to Glu271 residue of LTA4H. They supported their prediction by testing and confirming [6]-gingerol inhibitory effect on colorectal cancer cells [42]. The gene discussed is LTA4H; the disease is cancer.