We searched a few studies that reported cytoplasmic expression of C-MYC in leukemia cell line, endometrial carcinoma, and high grade B cell lymphomas (Craig et al., 1993; Geisler et al., 2004; Ruzinova, Caron & Rodig, 2010), but all the authors defined the cytoplasmic C-MYC status as negative or positive, which was different with our four-categories evaluation methods (0, +, + +, + +  +). The gene discussed is MYC; the disease is leukemia.