As shown in Table 1, patients’ age, WBC, LDH level, as well as cytoplasmic C-MYC expression and Ki-67 index demonstrated a significantly positive correlation with risk stratification (P = 0.000, 0.029, 0.000, and 0.000, respectively), while CD8+TIL in tumor microenvironment negatively correlated with risk stratification of patients (P = 0.006). The gene discussed is MKI67; the disease is neoplasm.