ACHE and Alzheimer disease: As PMR was proved to inhibit the activity of acetylcholinesterase (AChE) and 2,3,5,4′-tetrahydroxystilbene-2-O-β-D-glucopyranoside (THSG) and emodin-8-O-β-D-glucoside (EG) as the main components in PMR were proved to decrease AChE activity and THSG increased the expression of protein phosphatase-2A (PP-2A) and microtubule associated protein-2 (MAP-2) in the hippocampus of model rats, PMR was suggested to have the potential for antiaging such as Alzheimer's disease treatment [4, 5].