Hypersensitivity: MDA-MB-231-BCRP cells vs. MDA-MB-231-pcDNA cells (D.R. < 0.70) (Kuete et al., 2014a); induces apoptosis in Jurkat human T-cell leukemia cells through DNA fragmentation, MMP alteration and caspase-3 activation as well as downregulation of the anti-apoptotic Bcl-2 protein (Miyoshi et al., 2003). The gene discussed is ABCG2; the disease is T-cell leukemia.