Hypersensitivity: HCT116 (p53−/−) cells vs. HCT116 (p53+/+) cells (D.R. 0.77); Normal sensitivity: MDA-MB-231-BCRP cells vs. MDA-MB-231-pcDNA cells (D.R. 1.09); U87MG.ΔEGFR cells vs. U87MG cells (D.R. 1.10); induces apoptosis in CCRF-CEM leukemia cells via disruption of the MMP and increase in ROS production (Kuete et al., 2015a). This evidence concerns the gene ABCG2 and leukemia.