These data confirm that the oligoclonal CD8+ T-cell populations in TCL generated from paired NAWM and WML of the same MS patient were clonally distinct (patients #2, #4 and #8; Online Resource 6), whereas CD8+ T cells in paired WML-TCL of multiple MS patients showed a strong clonal overlap (patients #5, #6, #7 and #9; Online Resource 6). This evidence concerns the gene CD8A and myeloid sarcoma.