Previous studies, both on EAE and MS patients, support a key role of pathogenic T cells directed to various cMSAg including glia- (KIR4.1, S100B), oligodendrocyte- (MAG, MBP, MOG) and neuron-specific proteins (CNTN2 and NFASC) [17–19]. Here, MBP is linked to myeloid sarcoma.