Liangos et al. studied urinary KIM-1 and N-acetyl-β-d-glucosaminidase (NAG) in 201 patients with established AKI and found that elevated levels of urinary KIM-1 and NAG were significantly associated with the clinical composite endpoint of death or dialysis requirement, even after adjustment for disease severity or comorbidity [49]. The gene discussed is HAVCR1; the disease is acute kidney injury.