Likewise, in the lung adenocarcinoma tissue specimens, the expression level of YB-1 and MACC1 were also much higher than in the normal lung tissues adjacent to tumor lesions (Figure 5C), and YB-1 expression was positively correlated with MACC1 expression (Figure 5E, R2=0.8136, p<0.0004). The gene discussed is MACC1; the disease is lung adenocarcinoma.