Then we selected several EZH2 potential targets (p15, p16, p21, p53, p57, KLF2, E-cadherin, FBXO32, BRCA1, TRAIL, NKD2, DDIT3, DAB2IP, PLK3, CLDN14, LATS2, PTEN) with tumor-suppressor function that had been reported before, and postulated that they might be related to the contributions of UCA1 to GBC progression. Here, UCA1 is linked to neoplasm.