Since high-grade serous ovarian tumors express higher levels of CA125 than the nonserous mucinous ovarian tumors [43, 44], our finding is consistent with the notions that at least some of the high-grade serous ovarian tumors originate in the fallopian tube and nonserous mucinous tumors might develop from the ovarian surface epithelium or cortical inclusion cysts. The gene discussed is MUC16; the disease is mucinous neoplasm.