Moreover, it has been proved in our previous statements that serum levels of ST2 and IL‐33 are high in AMI patients with MACEs, and a combined use of ST2 and NT‐proBNP can improve the predicting ability of heart failure death; when the serum levels of ST2 and IL‐33 are high, the AMI severity as well as Gensini score is elevated, in other words, the serum levels of ST2 and IL‐33 are positively correlated with Gensini score of AMI 27, 34. The gene discussed is IL33; the disease is heart failure.