The latter will be achieved through further development of the ‘breast and ovarian analysis of disease incidence and carrier estimation algorithm’ (BOADICEA) which presently computes BRCA1 and BRCA2 mutation carrier probabilities and future risks of developing breast and ovarian cancer on the basis of explicit disease inheritance patterns, family history and genetic testing information [9–13]. Here, BRCA2 is linked to ovarian carcinoma.