Based on the data obtained via this method, the main canonical pathways that were overrepresented in the TH vs. YH and TL vs. YL comparisons were related to hepatic fibrosis/hepatic stellate cell activation (FN1, CTGF, CCL5, A2M, and FGF1, and COL1A2, CTGF, AGT, and COL3A1; P = 3.85E-02 and P = 2.58E-02, respectively), and glucocorticoid receptor signaling in TH vs. YH (DUSP1, SLPI, CCL5, and A2M, and DUSP1 and AGT; P = 1.82E-01 and P = 3.66E-01, respectively). Here, FGF1 is linked to Hepatic fibrosis.