TAP1 and ovarian carcinoma: In the treated group, CaCo2 cells showed significant upregulation of B2M, TAP1 and TAPBP. Colo201 cells showed significant upregulation of B2M, LMP2, TAP1 and TAPBP. 23 ovarian cancer cell lines were also investigated [3] and demonstrated upregulation of antigen processing and presentation genes (four representative cell lines are presented in S2 Fig).