The four upregulated microRNAs in patient blood (miR-127-3p, miR-329-3p, miR-487b-3p and miR-204-5p) cumulatively target BCL6, TrkB, KDM1A and ALDH1A3, all of which have been shown to be important regulators in PCa [24,25,26,27,28,29,30,31,32,33,34]. The gene discussed is KDM1A; the disease is posterior cortical atrophy.