For example, Kim et al. [46] reported that thymoquinone relieves the inflammatory response and hepatic fibrosis through the activation of the LKB1/AMPK signaling pathway, and honokiol, a bioactive compound obtained from the stem bark of Magnolia officinalis, protects against liver injury caused by hypoxia/reoxygenation and hepatotoxicants via an LKB1-dependent pathway [47]. Here, STK11 is linked to Hepatic fibrosis.