CSF2 and neoplasm: With the aim of inducing adaptive and innate immune responses against micrometastatic foci, targeting both HLA-positive and HLA-negative tumor cells, we developed the CSF-470 vaccine (Vaccimel), an inert scaffold of four lethally irradiated allogeneic CM cell lines, coadjuvated with BCG and recombinant human granulocyte macrophage-colony stimulating factor (rhGM-CSF).