VEGF-B delivery into myocardium with adenoviruses in rodent or pig hearts consistently produces an increase in the density or diameter of the myocardial capillaries, and AAV-VEGF-B delivery appears to protect the heart against ischemia-, pacing-, or load-induced cardiomyopathy (Bry et al., 2014). The gene discussed is VEGFB; the disease is ischemia.