In gliomas, PPAR gamma agonists inhibit cell proliferation by induction of cell-cycle arrest in G0/G1 phase (Zang et al., 2003; Liu et al., 2004; Chearwae and Bright, 2008), and reduction of the proportion of cells entering S-phase (Zang et al., 2003; Liu et al., 2004; Chearwae and Bright, 2008). The gene discussed is PPARG; the disease is central nervous system cancer.