In numerous studies, the nuclear translocation of beta-catenin in glioblastoma has been shown (Sareddy et al., 2009; Yang et al., 2010; Chen et al., 2011; Liu C. et al., 2011; Liu X. et al., 2011; Zhang N. et al., 2011; Kaur et al., 2013; Riganti et al., 2013). This evidence concerns the gene CTNNB1 and glioblastoma.