Aberrant WNT/beta-catenin signaling has a key role in the development of glioblastoma (Palos et al., 1999), including cell proliferation (Pulvirenti et al., 2011), cell apoptosis inhibition (Satoh and Kuroda, 2000), and cell invasion (Roth et al., 2000). Here, CTNNB1 is linked to glioblastoma.