IL6 and glaucoma: To better elucidate the impact of IL-6 signaling on RGC axonopathy in glaucoma, we comprehensively examined and compared optic nerve morphology, visual acuity, active axonal transport, and retinal glial reactivity in IL-6 deficient (IL-6-/-) and wildtype (WT) mice with 8 weeks of unilateral or bilateral microbead-induced glaucoma (microbead occlusion model).