PIK3CA and serous adenocarcinoma: JHUCS-1 cells were found to have an overlapping mutational landscape with mutations in genes seen in both endometrioid and serous adenocarcinomas, including TP53, FBXW7, PPP2R1A, PIK3CA, ARID1A, PTEN, and CTNNB1. SNU-685 cells were found to have mutations in TP53 and PPP2R1A, similar to serous adenocarcinomas.