GRIN1 and ischemic stroke: To determine whether glycine-GluN1 binding mediates glycine-induced functional recovery in the ischemic stroke animals, in the same experimental conditions, L-689560 (0.1 mg/100 g, ip) was injected with MK-801 (8.0 μg/100 g) and strychnine (1.2 μg/100 g) at 30 min prior to glycine treatment.