At the protein level, the half-life of PIM1 varies between 5 to 15 minutes in primary cells7 and is found to be increased up to 100 minutes in certain tumour cells such as K562, and BV173 expressing the BCR-ABL fusion protein, potentially through HSP90-mediated protection from ubiquitylation and subsequent proteasomal degradation8, 9. Here, PIM1 is linked to neoplasm.