Interestingly, no obvious difference was observed in vimentin and α-SMA positivity in the tumor stroma between tumors derived from EBC1 cells only and those derived from EBC1 cells with HFL1 or MRC5 cells at 8 weeks (data not shown) or at an even earlier time point (at 2 weeks) after inoculation (Fig. 1d). The gene discussed is ACTA1; the disease is neoplasm.