Comparison of the 18 CCP2-negative patients in each group showed that p48/p55 vimentin was lower in PR patients (5.6% vs. 38.9%; p = 0.04) and that PR patients had a lower mean number of positive specificities (0.17 ± 0.5 PR vs. 0.56 ± 0.6 RA; p = 0.04). This evidence concerns the gene AGBL2 and rheumatoid arthritis.