In multiple logistic analysis, the presence of LEAD was defined as the dependent variable and age, gender, BMI, W, SBP, diastolic blood pressure (DBP), HbA1c, HOMA2-IR, TC, TG, HDL-c, LDL-c, CRP, GFR, Ca, P, serum FGF23 levels, diabetes duration, current smoking, current alcohol use, anti-hypertensive therapy, and lipid-lowing therapy were defined as independent variables. This evidence concerns the gene FGF23 and diabetes mellitus.