Data showed that several CpGs within or near genes involved in inflammatory processes (Interleukin 17 Receptor A (IL17RA)), regulation of gene expression (miR124–3) and neuronal excitability and development/maintenance of the nervous system (Potassium Voltage-Gated Channel Subfamily Q Member 2 (KCNQ2)) were differentially methylated, either in BPD compared with MDD or in relation to the severity of childhood maltreatment. The gene discussed is KCNQ2; the disease is Borderline personality disorder.