A similar analysis of 17 EBV+ endemic Burkitt lymphomas [31] indicated HIF-1α mRNA was, on average, nine-fold more abundant than HIF-2α mRNA (range 2-fold to 19-fold), with HIF-3α mRNA detectable above background in only one of these 17 tumors (at 1/20th of the HIF-1α level). Here, HIF3A is linked to Burkitt lymphoma.