INS and type 2 diabetes mellitus: In sections of pancreatic tissue from 4 out of the total 12 T2D donors (but in none of those from ND subjects), and within small clusters of cells with islet-like appearance scattered in the acinar tissue, a few cells were observed, containing both zymogen-like and insulin-like granules in their cytoplasm (Fig 1C and 1D, Figs 2 and 3).