HeLa cells overexpressing human wild-type tau (HeLa/tau cells), human neuroblastoma SH-SY5Y cells, and primary neuronal cells were treated with LP at increasing concentrations (0, 2.5, 5, and 10 mM) for 12 h, followed by analysis of tau and/or GSK3β phosphorylation by WB. The gene discussed is MAPT; the disease is neuroblastoma.