To assess whether the contribution of BST2 to cisplatin resistance is specific to the CNE2 cell line and its derivative cell line, we next investigated the effect of BST2 on cisplatin resistance in another two NPC cell lines, HONE1 and HNE1, by knocking down BST2 expression with siRNAs and determining the IC50 of cisplatin by an MTT assay. Here, BST2 is linked to nasopharyngeal carcinoma.