These findings are also supported by the report of Guatelli J and colleagues27 but somewhat contradict those of Galao RP et al.35 Overexpression of the BST2 Y6,8A mutant did not increase platinum resistance in NPC cells, whereas overexpressing the ΔGPI mutant and wild-type BST2 had similar effects on platinum resistance, corroborating the effects of these constructs on NF-κB activation. This evidence concerns the gene NFKB1 and nasopharyngeal carcinoma.